Pennsylvania State Police say a 28-year-old Maine man called 911 about a road-rage attack before dying from his wounds.
They say 28-year-old Timothy Davison called from Interstate 81 near Maryland early Saturday to say someone in a pickup truck was firing on him.
Police say Davison was then forced into a median before the assailant approached and fired several rounds at him.
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State police are searching for a Ford Ranger-style pickup. They say the vehicle may be blue and may have damage to the driver's side.
They say Davison, who was from Poland, Maine, died at a York hospital following the 2:10 a.m. attack.
Police say the shooting occurred in the southbound lanes in Antrim Township, about 10 miles north of Hagerstown, Maryland.