Host Stephen Colbert took an interest in the space agency's online naming poll for Node 3. The comedian quipped: "I certainly hope NASA does the right thing. Just kidding, I hope they name it after me."
Voters could choose from four NASA options -- Serenity, Legacy, Earthrise and Venture -- or suggest their own. Colbert was the top choice -- earning more than 230,000 votes out of 1 million -- but NASA reserved the right to be the final arbiter.
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Astronaut Sunita Williams will appear on Tuesday's episode for the naming announcement.
Mission Control is at Johnson Space Center in Houston, where astronauts train.