The action tale about a team that sneaks into people's dreams is DiCaprio's biggest opening weekend, topping his previous best of $41.1 million for last winter's "Shutter Island."
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"Inception" falls far short of director Christopher Nolan's best, though. Nolan is the man who directed the Batman blockbuster "The Dark Knight," which opened over the same weekend two years ago with a record $158.4 million.
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