LeBron James watched as the Cleveland Cavaliers couldn't quite make history.
With their superstar, All-Star guard Mo Williams and other regulars resting for the playoffs, Cleveland lost for just the second time on their home floor this season, 111-110 in overtime Wednesday night to the Philadelphia 76ers.
That left the Cavs at 39 home wins -- one shy of tying the 1985-86 Boston Celtics' all-time home record of 40-1.
Andre Miller scored 30 points and Andre Iguodala 24 for the Sixers, who snapped a six-game losing streak. Philadelphia earned the No. 6 spot in the Eastern Conference playoffs, where it will meet the Orlando Magic.
Daniel Gibson scored 28 for the Cavaliers, the No. 1 overall seed. Cleveland will play Detroit in the first round.
The Cavs went into their finale with nothing to gain, so coach Mike Brown, not willing to risk any injuries, sat James, Williams, center Zydrunas Ilgauskas and forward Joe Smith. Delonte West and Anderson Varejao -- Cleveland's two other starters -- began the game but didn't play in the second half.
But even with their reserves, the Cavs gave the Sixers all they could handle.
Philadelphia, which trailed by 12 at halftime, rallied and led 98-95 with 4.4 seconds left in regulation on two free throws by Miller.
But with the Cavaliers' second home loss less than one tick away, Gibson swished a 3-pointer from the top of the key to tie it at 98 with 0.6 seconds left. The Sixers quickly called time, and when Gibson ran to the other end of the floor, he was greeted by James, who slapped hands with his sharpshooting teammate.
Philadelphia couldn't get off a final shot before the horn, and as the teams were getting ready for overtime, James and Williams joined the Cavs' dance team in the center of the floor for an impromptu number.
But in overtime, Miller and Iguodala took turns scoring or getting to the foul line as the Sixers attempted 41 free throws to 12 for Cleveland.
Miller's two free throws made it 111-108 with 15.8 seconds before Gibson hit a layup to get the Cavs within a point. Miller was fouled, and Cleveland had new life when the former Cavs guard missed two free throws with 4.3 seconds left.
Gibson took an inbounds pass, but stumbled trying to make a cut and the clock expired before he could recover and get to his feet.
Thaddeus Young added 20 points and Lou Williams 19 for the Sixers, who went 0-3 against the Magic during the regular season.
Philadelphia center Samuel Dalembert strained his right shoulder in the first quarter and did not return.
Wally Szczerbiak scored 21 and Sasha Pavlovic 21 for the Cavs.
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Copyright AP - Associated Press