The Veep's eldest son was being treated at Christiana Hospital in Newark, Del., the White House said.
"Biden was admitted this morning to Christiana Hospital in Newark, Del. after having what we believe to be a mild stroke," said Dr. Timothy Gardner, Medical Director of the Center for Heart and Vascular Surgery at Christiana Care Health System.
The 41-year-old Iraq War veteran was in good spirits and talking with family members including the Vice President, Jill Biden and Beau's wife Hallie, NBC Philadelphia learned.
"(Biden) is fully alert, in stable condition and has full motor and speech skills," Dr. Gardner said. "We expect him to make a complete recovery."
Beau is being transferred to Thomas Jefferson University Hospital in Philadelphia for further observation, the White House said.
Vice President Biden watched intently as his son was loaded into the back of a ambulance. Mr. Biden and the rest of the family followed the ambulance as it made its way up to Philadelphia Tuesday afternoon.
Police shut down Center City around Jefferson Hospital as Beau arrived just after 6 p.m.
News of the Del. Attorney General spread quickly through the First State as his peers offered well wishes.
"Beau Biden is a great leader with a great family, and I'm glad they're with him right now," said Delaware Gov. Jack Markell.
There is a history of neurological issues in the Biden family. Joe was away from the Senate for seven months in 1988 after undergoing surgery for brain aneurysms.
Beau, a member of the Delaware National Guard, became the First State's attorney general in 2007. He had considered running for the Senate seat his father held before becoming vice president, but ultimately decided against it.
The Biden Family has had their share of personal tragedy over the years. In 1972, Joe lost his wife and infant daughter when a tractor-trailer broadsided their station wagon when they were out getting a Christmas tree. Beau and his brother Hunter were critically injured but recovered.
The elder Biden's emotional Senate swearing-in ceremony in 1973 included his two young sons.
Beau is married with two young children. He has worked as an attorney in private practice. He also worked for the Justice Department between 1995 and 1997 and as an assistant U.S. attorney from 1997 to 2002.
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