Jordan Matthews will not play Sunday against the Bengals after missing practice all week with an ankle sprain, according to NFL Network's Ian Rapoport.

The #Eagles are not expecting WR Jordan Matthews (ankle) to play vs. #Bengals, sources say. He didn't practice on Friday.— Ian Rapoport (@RapSheet) December 4, 2016

Matthews is the Eagles' leading receiver with 57 catches for 686 yards and three touchdowns. The team has called him a game-time decision.

Second-year receiver Nelson Agholor will reportedly be inserted back into the lineup. If Matthews doesn't play the Eagles will have only four healthy receivers active on Sunday: Agholor, Dorial Green-Beckham and undrafted rookies Bryce Treggs and Paul Turner.