The Eagles (3-1) are riding high after returning from Los Angeles with their second road win of the season.
Meanwhile, the Cardinals (2-2) come to the Linc after an 18-15 overtime win against the 49ers at home. In fact, both of the Cardinals' wins have come in overtime.
This Arizona team isn't the same one that won 13 games in 2015. The Cardinals have fallen off a little bit, going 7-8-1 last season. But they still have good players at key positions.
Here are five matchups to watch on Sunday:
Jared Veldheer vs. Brandon Graham The Cardinals' right tackle has struggled this season and is going against the Eagles' best edge rusher. Veldheer has given up two sacks, three QB hits and 16 QB hurries so far this season, according to ProFootballFocus. He really struggled against Cowboys DE Demarcus Lawrence.
On a conference call with Philly reporters earlier this week, Cardinals head coach Bruce Arians said QB Carson Palmer is in the best shape he's ever been.
"We've just got to quit getting him hit so much," Arians said.
Palmer has been sacked 17 times through four games. That's more than any other quarterback in the NFL and just the eighth time in the last 10 years a QB has been sacked that much through four games.
Meanwhile, the Eagles had eight sacks in the first two weeks of the season but have had just two over the last two weeks. Graham might have a chance in this one.
Cardinals' running backs vs. Eagles' run defense The Cardinals have the worst rushing offense in the NFL, averaging 57.0 yards per game. They're clearly missing David Johnson, who is out with a wrist injury. In his place, the Cards are using a combination of senior citizen Chris Johnson and former starter Andre Ellington. It hasn't gone that well.
On the flip side, the Eagles have the second-best run defense in the league, giving up just 70.8 yards per game.
Arians said he would like to be more balanced and run the ball but fourth quarters have dictated their lack of run game. They might try to get it going in Philly on Sunday but it won't be easy.
Larry Fitzgerald vs. Patrick Robinson Fitzgerald is 34 years old and is still the Cardinals' best receiver. It's pretty insane. This season he has 26 catches for 276 yards and two TDs. He's on pace for what would be his ninth 1,000-yard season and his third straight. He should be slowing down, but the move into the slot a couple years ago has really given his career some extra length.
Arians said most teams elect to use their slot cornerback against Fitzgerald and if the Eagles do that, it means Robinson will give it a go. Robinson came in as an outside starter for the Eagles but got bumped inside after they acquired Ronald Darby. Robinson's been great there so far this season.
Now, in the past, Malcolm Jenkins has enjoyed this matchup against Fitzgerald. And there's a chance he might play there some on Sunday, but it'll depend on the health of Corey Graham. Graham has missed the last two games with a hamstring injury. If Jenkins moves into the slot, the Eagles need Graham to take his spot at safety.
"It would be a huge benefit to get Corey in there," Pederson said. "And it does give Malcolm flexibility to move down into the box and play some nickel if need be."
Alshon Jeffery vs. Patrick Peterson Jeffery has been somewhat underwhelming through the first quarter of his first season with the Birds. He has 17 catches for 215 yards and two touchdowns. He's on pace for 68 catches, 860 yards and eight touchdowns. Not bad, but not WR1-type numbers either.
And this week it won't get any easier. Peterson is one of the NFL's best cover corners. This is his seventh NFL season and he's already been to the Pro Bowl six times and has been all All-Pro three times. Expect to see him stick with Jeffery all afternoon on Sunday.
Jason Peters vs. Chandler Jones The Cardinals lost Markus Golden for the season to an ACL tear but they still have Jones, their best pass-rusher. He already has four sacks this season and is on pace for his third straight double-digit sack season. Jones is a handful.
Most of Jones' snaps this season and all four of his sacks have come from the right side, which means he'll be going against Peters a lot on Sunday. But Peters has been incredible through four games. He has yet to give up a sack or a QB hit and has given up just four QB hurries.
So maybe, the Cardinals want to move Jones over the right tackle. The problem there is that Lane Johnson has been nearly as good. Either way, it'll be a good battle.