Phillies starter Joe Blanton (0-2) gave up three runs and eight hits in six innings against the Brewers Wednesday night. He has lost two straight outings after going unbeaten in his first 17 starts with Philadelphia.
J.J. Hardy had a solo homer for the Brewers, who snapped a six-game losing streak against the Phillies in the regular season.
Looper (2-0) allowed five hits and walked two. Mark DiFelice and Carlos Villanueva each tossed a perfect inning and Todd Coffey pitched out of trouble in the ninth to earn his second save.
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After striking out Ryan Howard, Coffey allowed a solo homer to Jayson Werth and a single to Raul Ibanez. He retired Pedro Feliz on a fielder's choice grounder before pinch-hitter Matt Stairs singled. Coffey then struck out pinch-hitter Chris Coste to end it.
Only three runners reached second base against Looper.
On a chilly, rainy night when strong winds made fly balls adventurous, there wasn't much offense.
Hardy hit a 3-2 pitch into the left-field seats to give Milwaukee a 1-0 lead in the fifth. Cameron lined a two-out double to make it 3-0 an inning later.
Prince Fielder reached on an infield single in the second inning when first baseman Howard overran his popup that got caught in the strong wind.
Ryan Braun lined a single off the left-field wall in the fourth and was thrown out trying to stretch it into a double on a perfect throw by Ibanez.
The series wraps up Thursday afternoon at CPB.