In the episode of the popular HBO comedy, David's recent intake of vitamins causes him to have a strong stream of urine that results in some errant drops falling on a Jesus painting hung in a bathroom -- giving the impression that Christ is actually shedding a tear.
The accident, and David's inexplicable instinct not to clean it, leads to a hilarious series of events where the owner of the portrait believes she's in possession of a miracle. As usual, the unscrupulous David character doesn't 'fess up to the splash until it's almost too late.
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"Was Larry David always this crude? Would he think it's comedic if someone urinated on a picture of his mother?" Donohue said in a statement. "This might be fun to watch, but since HBO only likes to dump on Catholics (it was just a couple of weeks ago that Sarah Silverman insulted Catholics on 'Real Time with Bill Maher') and David is Jewish, we'll never know."
Donohue also suggested that David, who co-wrote and produced "Seinfeld," was scraping the bottom of the comedy barrel and "should quit while he's ahead."
"When David and Jerry Seinfeld (playing himself) are asked if they ever experienced a miracle, David answers, 'every erection is a miracle,'" Donohue's statement continued. "That's what passes for creativity these days."
HBO fired back with a statement asking everyone to calm down, pointing to the show's consistently irreverent tone.
"Anyone who follows Curb Your Enthusiasm knows that the show is full of parody and satire," the statement read. "Larry David makes fun of everyone, most especially himself. The humor is always playful and certainly never malicious."