"Alice In Wonderland" director Tim Burton was on stage in Hall H at the San Diego Convention Center when he reportedly said he wanted his "imaginary friend" to join him on the stage.
U.S. & World
Stories that affect your life across the U.S. and around the world.
Depp then appeared and the crowd erupted with cheers and screams of joy.
The actor only stayed for a brief moment, waving at the screaming crowd at the Disney 3-D panel.
Depp's appearance flooded Twitter with excited Tweets from inside the crowd.
"Tears wiped over Johnny Depp. Decibel level to 11. This is CRAZY fandom," one user wrote. While another claimed, "Women are chanting 'I love you Johnny!' Men are chanting 'I love you Johnny!!'"
Related Content from AccessHollywood.com:
VIEW THE PHOTOS: Johnny Depp: Hollywood's Man Of Many Faces
PLAY IT NOW: Comic-Con 2009: Kristen, Robert & Taylor Talk 'New Moon' - Part I
PLAY IT NOW: Comic-Con 2009: Seth Rogen Unveils 'Green Hornet's' Black Beauty