Two men, armed with shotguns, entered the Dunkin' Donuts store at Harbison and Torresdale Avenue in Wissinoming early Thursday.
Police say one of the men was wearing a blue bandana and a gray hoodie. They do not have a description of the second man.
They gunmen made off with an undetermined amount of cash.
Investigators are checking if this could be related to a string of Dunkin' Donuts robberies in early July.