SANTA CLARA, Calif. -- Ezekiel Elliott ran for 138 yards and a touchdown and Dak Prescott threw for two scores to help the Dallas Cowboys overcome an early 14-point deficit to beat the San Francisco 49ers 24-17 on Sunday.

The Cowboys (3-1) fell in a 14-point hole early in the second quarter before taking over the game behind a pair of rookies who have helped the team get off to a fast start this season with starting quarterback Tony Romo sidelined by a back injury.

Prescott threw for 245 yards and had a 20-yard touchdown pass to Terrance Williams and a 4-yarder to Brice Butler to tie the game at the half.

Elliott then took over with 96 yards rushing in the second half, including a 1-yard run that gave Dallas the lead for good late in the third quarter.

Blaine Gabbert got off to a fast start to help San Francisco (1-3) take the early lead but struggled to generate any offense after that. Gabbert finished 16 for 23 for 196 yards with one touchdown and one interception .

He had a chance to lead a late tying drive but he threw a 3-yard pass to Torrey Smith on fourth-and-6 from the Dallas 35 to end hopes at a comeback (see full recap).

Redskins pull away from Browns late, win 31-20
LANDOVER, Md. -- Kirk Cousins threw three touchdown passes, including two to tight end Jordan Reed, and the Washington Redskins cashed in on several trips to the red zone to beat the Cleveland Browns 31-20 on Sunday.

The Redskins (2-2) scored four red zone touchdowns against the Browns (0-4) after going 3 for 14 in their first three games of the season. Cousins connected with Reed for 8- and 9-yard touchdowns, Chris Thompson for a 5-yard score, and running back Matt Jones scored from 1 yard out as part of his 117-yard performance.

Jones eclipsed the 100-yard mark for the first time this season, and Cousins finished 21 of 27 for 183 yards and also had an interception.

Browns running back Isaiah Crowell ran for 112 yards and a touchdown, and Cody Kessler was 27 of 38 for 215 yards, one touchdown and one interception. But turnovers on three consecutive second-half possessions cost Cleveland a chance at its first victory of the season.

Brees, Saints stun Chargers in final minutes for 35-34 win
SAN DIEGO -- Drew Brees threw two touchdown passes in the final 4 minutes, 50 seconds to rally the New Orleans Saints to a stunning 35-34 victory on Sunday against Philip Rivers and the San Diego Chargers, who blew a 13-point lead by committing two crucial turnovers.

Brees overcome two interceptions to win in his return to San Diego, where he played his first five NFL seasons before being allowed to leave as a free agent. It was also the first win this season for the Saints (1-3).

After the final gun, Brees ran over to the stands and greeted Saints fans.

With the Chargers trying to protect a 34-21 lead, Melvin Gordon fumbled and Darryl Tapp recovered at the San Diego 13, setting up Brees' 5-yard TD pass to Michael Thomas on fourth-and-2 to pull to 34-28 with 4:50 to go.

Travis Benjamin then fumbled after a reception and Nate Stupar recovered at the San Diego 31. Seven plays later, fullback John Kuhn scored his third TD of the game, on a 1-yard run. The PAT made it 35-34.

Rivers, who was Brees' understudy for his first two NFL seasons, was intercepted by B.W. Webb with 1:10 to go.

It was the third time this season the Chargers (1-3) blew a late lead.

Bills hand Patriots first loss in 16-0 shutout
FOXBOROUGH, Mass. -- Buffalo took advantage of sloppy, Tom Brady-less New England to hand the Patriots their first home shutout at Gillette Stadium, winning 16-0 Sunday.

It was the first loss of the season for New England (3-1), which was playing its final game before Brady returns from his four-game "Deflategate" suspension. The Patriots, who moved into Gillette Stadium in 2002, were last blanked at home 6-0 by the New York Jets in 1993 at Foxboro Stadium.

Tyrod Taylor connected with LeSean McCoy for a 7-yard touchdown pass in the first quarter, Dan Carpenter added three field goals for Buffalo (2-2).

It was Buffalo's second win in its last 16 visits to Foxborough. Including his tenure with the New York Jets, it gave Bills coach Rex Ryan his first regular-season road victory over Bill Belichick in eight tries. The last Bills' shutout win away From Orchard Park was 23-0 over Washington in a Buffalo "home" game at Toronto on Oct. 30, 2011.

After struggling to maintain drives and finding a run-pass balance, Taylor was spot-on Sunday. He finished 27 for 39 for 246 yards, and directed a unit that was 7 for 15 on third downs. The Bills had been 10 of 36 combined in the first three games.

Buffalo's defense also carried over its dominant effort from its 33-18 win over Arizona, sacking rookie Jacoby Brissett three times.

Brissett made his second consecutive start in place of Jimmy Garoppolo (sore right shoulder). But Brissett, playing a week after injuring his right thumb, struggled to find the command he had in leading the Patriots to a 27-0 win over the Texans. New England finished 1 for 12 on third downs and managed just 277 total yards.

After managing to reach the red zone with four drives in their first three games, the Bills did it on their first two series Sunday.

Their first possession, a 12-play, 65-yard drive, ended in Taylor's touchdown strike to McCoy. The second stretched 52 yards over 10 plays and was capped by the first of two first-half field goals by Dan Carpenter.

Jaguars hold off Colts, 30-27, in London
LONDON -- Blake Bortles threw for two touchdowns and ran for another as Jacksonville held off a furious Indianapolis Colts rally to win 30-27 in London for the Jaguars' first win of the season.

Sunday's victory at a raucous Wembley Stadium elevated Jacksonville into a tie with Indianapolis at 1-3 in the AFC South.

Andrew Luck led the Colts on three fourth-quarter touchdown drives to rattle the Jaguars' nerves. But his fourth-and-1 pass at the Jacksonville 49 with 1:36 remaining fell from the hands of tight end Dwayne Allen to preserve the victory for under-fire Jaguars coach Gus Bradley.

The Jaguars got a semblance of a running game going for the first time this season. T.J. Yeldon carried 13 times for 68 yards and Bortles added seven scrambles for 36 yards, including a 1-yard run that put Jacksonville ahead 14-6 midway through the second quarter.

The Colts repeatedly self-destructed on offense with dropped balls and another costly Luck interception that led to Jacksonville's opening touchdown. The Colts proved just as reckless on defense as pass interference and unnecessary roughness penalties extended three Jacksonville scoring drives.

The Jaguars led 23-6 after three quarters before the Colts mounted a tenacious comeback.

Their first touchdown drive of the final period was aided by an end zone pass interference on safety Jonathan Cyprien. Frank Gore (16 carries for 68 yards) punched the ball through on the next play to complete a nine-play, 75-yard drive barely seconds into the final period.

After a Jacksonville punt, Luck led a 12-play, 78-yard touchdown drive capped by his rollout scoring toss to T.Y. Hilton alone in the right corner of the end zone.

But Bortles found Allen Hurns on a short out route. Hurns made reserve cornerback Rashaan Melvin miss, then cut inside and through the defense for a 42-yard touchdown that seemingly put the Jaguars safely ahead 30-20 with 5:31 left.

But Luck pulled the Colts back to 30-27 barely two minutes later. A defensive miscue by Jaguars rookie Jalen Ramsey left Phillip Dorsett streaking alone to haul in a 64-yard touchdown throw (see full recap).