The Children's Hospital of Philadelphia and Temple University received a joint $4.3 million grant from the National Institute of Mental Health to investigate new methods for eradicating HIV that lurks in brain cells after patients receive conventional antiviral treatments.
Dr. Steven D. Douglas, a professor of pediatrics and chief of immunology at CHOP, and Jay Rappaport, a professor of neuroscience and neurovirology at the Temple University School of Medicine, are co-principal investigators of the four-year grant.
"This program represents a fresh look into a long-standing problem in HIV treatment — reservoirs of HIV within immune cells," Douglas said. "While current antiretroviral treatments can reduce the virus to undetectable levels, HIV persists latently inside cells. If drug treatment is interrupted, the virus comes surging back." Read more about the story on PBJ.com
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